Instructions: This assignment is based on the learning objectives and concepts as described in the Unit Learning Guide. There are 9 questions worth a total of 64 marks and this assignment will contribute 64% towards the total assessment for this subject.
Task: 401173 Introduction to Clinical Epidemiology Assignment
Answer questions 1-2 based on the following scenarios:
Question1:Fred, a 65-year-old obese man with a history of type 2 diabetes mellitus and hypertension presents to the GP practice for a follow-up appointment. During the consultation, he asks whether there is a better medication to glicazide and metformin, his oral hypoglycemic medications, which he has been taking to control his blood sugar. His friend has recently been put on a newer oral hypoglycemic medication (Liraglutide, a glucagon-like peptide-1 analogue), which has been shown to help with weight management in patients with diabetes and obesity. Fred has been finding it very difficult to lose weight for a few years now as he has tried various lifestyle modifications. He asks whether the new oral hypoglycemic medications could be an option for him in weight reduction. [2 marks]
- Write a focused research question for this particular problem that will help you organize a search of the literature for an answer (use the PICO elements as appropriate).
Question2: In the past 2 years, as an Infectious Disease Specialist in one of the tertiary hospitals in Australia, you have attended to 23 migrant patients who were referred by their General Practitioners with symptoms not typical of pulmonary tuberculosis. After taking a detailed history and performing appropriate physical examinations, as well as reviewing a range of relevant investigations, you clinically diagnosed and microbiologically confirmed that those patients have multi-drug resistance pulmonary tuberculosis (MDR-TB). The Public Health Department was notified of disease and the patients were managed accordingly. Now, you and some colleagues from Western Sydney University want to investigate the risk factors for MDR-TB. [2 marks]
- Write a focused research question for this particular problem that will help you organize a search of the literature for an answer (use the PICO elements as appropriate).
Question3: 401173 Introduction to Clinical Epidemiology Assignment-Western Sydney University Australia
Please select the single best answer for each of questions 3.I – VII
- Randomised controlled trials provide strong evidence that an observed effect is due to the intervention. One main reason is because [1 mark]
- When the study participants are randomized, many characteristics and potential confounders are likely to be evenly distributed in the groups[1 mark]
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